Different trips. My first one, I didn't recognize the visuals at the time and I smoked a bunch of weed that day with friends so I thought it wasn't even real acid--didn't know what it felt like. My second trip, I took a lot, and saw overlapping patterns of giant eyeballs on the walls, but I knew it was just hallucinations. I've never even come close to losing touch with reality, I can't imagine how much it would take to be unable to tell when something impossible happening (like foot-wide eyeballs opening and closing in diagonal rows on the walls) isn't real. Oh, it looks real, but you can say to yourself, "this isn't possible, so it's not real". The real trick is when something that would normally be crazy happens, like a car accident happening outside your house. It takes hard thought to be able to figure out if that's real or fake, and it ain't always real--a closed door can sound like a car crash, and then you look at the car and it's got a dent, but you hallucinate the dent is the whole front of the car, and then you run outside shouting, "oh my god is everyone okay?!" and then the people react to you shouting and then it looks like a crisis situation which just reinforces that an accident happened even though it didn't and now a couple people who just got out of the car have some guy running at them shouting half-coherent questions and--well, you can probably see how stuff can get out of hand. You have to have the presence of mind to think through all that stuff while you're more fucked up than you've ever been in your entire life.
The insights only came when I actually sat down and introspected while tripping--most of the time, I just used it as a party drug. That said, I don't think there's a significant difference between your 2nd and 40th trip. As another poster mentioned, there's a near 100% tolerance from one day to the next, but if you wait a couple weeks it goes away completely. Your first is different because a lot of people, their first time, don't even recognize that they're being affected until they're already on the way down. Strong visuals only happen when you're tripping hard, and the basic visuals (tracers, subtle movements in patterns, etc.) are easy to overlook because the mind-fuck is much stronger than the hallucinations at low-medium doses. You're more worried about the meaning of time and whether drinking orange juice is going to make you permanently insane than whether a leaf on the wallpaper might have moved a little.
I'm a nervous, introspective, pessimistic person, so tripping was always an ordeal for me. But, I'm also a pretty strong personality, so when I felt stuff slipping away I held on harder. Some people trip and fall over that edge, and act like someone in a fugue state, where there's no self-control, and that's the "bad trip" stuff you hear about--I bet a couple of times I had as much internal turmoil as some of those people who ran down the street naked, but I just sat in the corner blowing my cheeks out and scrubbing my hand through my hair every 2 minutes for 16 hours. Not that I'm particularly special or anything, I just never took enough to throw me over that edge, but I definitely got close a few times. I think a fair portion of the people who have the freakouts are looking for an excuse to act crazy, and LSD is one hell of an excuse. And then once you start acting weird, it's easier to keep acting weird and blame it on a bad trip than it is to just pull things together and go "woah, sorry dudes, I was freaking out, I'm good now." But, you've got the mind-fuck going on, so it's hard to rationally say, "oh man I'm taking this too far, it's time to own up to it."
But anyway, no single trip was a massive life-altering experience like I've heard of other people having. It just helped me look at stuff from a different angle, be more objective, and for some reason I can't explain, coming to the exact same conclusion while on acid had a much stronger effect than it would otherwise, but I always felt like the same person the next day and nobody ever said I'd changed or anything. I just actually felt like I really believed the conclusion I came to. Like, you say to yourself, "I need to get over this girl", but it doesn't stop you from missing that person. But, when I said that to myself while tripping
I know I went off on like 6 tangents here, but you seemed curious about the experience itself. For what it's worth, I don't think I could intentionally reproduce any of the positive stuff I got out of it, and that increased plasticity probably comes with increased risks, so if you're pursuing some goal other than general experience I wouldn't count on achieving anything in particular. I had positive experiences because I was in a positive environment, and had experienced people guiding me through things. If you're thinking of trying it out, do it with someone supportive, trustworthy, and experienced, because you're pretty much putting your brain in their hands. And for God's sake don't start out with more than 1-2 hits or 2-4 friends. If you want to challenge yourself, fine, but wait until you know what to fight and what to ride.
Source: http://rss.slashdot.org/~r/Slashdot/slashdotScience/~3/_d0sftufGX0/lsd-can-treat-alcoholism
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